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Gene : TT8 A. thaliana

DB identifier  ? AT4G09820 Secondary Identifier  ? locus:2118524
Name  ? TRANSPARENT TESTA 8 Brief Description  basic helix-loop-helix (bHLH) DNA-binding superfamily protein
TAIR Computational Description  basic helix-loop-helix (bHLH) DNA-binding superfamily protein;(source:Araport11)
TAIR Curator Summary  TT8 is a regulation factor that acts in a concerted action with TT1, PAP1 and TTG1 on the regulation of flavonoid pathways, namely proanthocyanidin and anthocyanin biosynthesis. Affects dihydroflavonol 4-reductase gene expression. It is thought that a ternary complex composed of TT2, TT8 and TTG1 is necessary for correct expression of BAN in seed endothelium. Also important for important for marginal trichome development. It binds the promoter of both AT3G26790 and AT1G28300.TT8 interacts with JAZ proteins to regulate anthocyanin accumulation. TT8 acts maternally to affect seed FA biosynthesis and inhibits seed FA accumulation by down-regulating a group of genes either critical to embryonic development or important in the FA biosynthesis pathway. TT8 represses the activities of LEAFY COTYLEDON1, LEAFY COTYLEDON2, and FUSCA3, the critical transcriptional factors important for seed development.
TAIR Short Description  basic helix-loop-helix (bHLH) DNA-binding superfamily protein
TAIR Aliases  AtTT8, BHLH42, TT8

6 Gene Rifs

1 Organism

52 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 4643  
Location: Chr4:6181881-6186523

Gene models - TT8 AT4G09820

? Gene models

Transcripts: 1  Exons: 7  Introns: 6 

Overlapping Features

? Genome features that overlap coordinates of this Gene

8 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
TT8_ARATH developmental stage Faint expression in buds and flowers. Increases during the very early stages of seed development, reaches a maximum at the globular embryo stage and stays high throughout seed formation.
TT8_ARATH function Transcription activator, when associated with MYB75/PAP1 or MYB90/PAP2. Involved in the control of flavonoid pigmentation. Plays a key role in regulating leucoanthocyanidin reductase (BANYULS) and dihydroflavonol-4-reductase (DFR). Not required for leucoanthocyanidin dioxygenase (LDOX) expression.
TT8_ARATH similarity Belongs to the bHLH protein family.
TT8_ARATH tissue specificity Buds, flowers and developing siliques, but not in leaves, stems and roots.

1 Proteins

Function

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

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Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets