DB identifier | AT3G60370 | Secondary Identifier | locus:2103366 |
Brief Description | FKBP-like peptidyl-prolyl cis-trans isomerase family protein |
TAIR Computational Description | FKBP-like peptidyl-prolyl cis-trans isomerase family protein;(source:Araport11) |
TAIR Curator Summary | Encodes an immunophilin, FKBP20-2, that belongs to the FK-506 binding protein (FKBP) subfamily functioning as peptidyl-prolyl isomerases (PPIases) in protein folding. FKBP20-2 has a unique pair of cysteines at the C terminus and was found to be reduced by thioredoxin (Trx) (itself reduced by NADPH by means of NADP-Trx reductase). The FKBP20-2 protein, which contains only two of the five amino acids required for catalysis, showed a low level of PPIase activity that was unaffected on reduction by Trx. Genetic disruption of the FKBP20-2 gene provide evidence that FKBP20-2 participates specifically in the accumulation of the PSII supercomplex in the chloroplast thylakoid lumen by means of a mechanism that has yet to be determined. |
TAIR Short Description | FKBP-like peptidyl-prolyl cis-trans isomerase family protein |