DB identifier | AT3G48190 | Secondary Identifier | locus:2100459 |
Name | ataxia-telangiectasia mutated | Brief Description | Serine/Threonine-kinase ATM-like protein |
TAIR Computational Description | Serine/Threonine-kinase ATM-like protein;(source:Araport11) |
TAIR Curator Summary | Encodes a homolog of the human ATM gene, which is mutated in ataxia telangiectasia, a chromosome instability disorder. Suppresses leaf senescence triggered by DNA double-strand break through epigenetic control of senescence-associated genes. Characterization of mutants suggest a role homologous recombination for DNA damage repair in response to ionizing radiation as well as during meiosis. The protein has kinase domains and shows kinase activity in orthologs. There is also evidence that ATM might be involved in the telomerase-independent process known as Alternative Lengthening of Telomeres. |
TAIR Short Description | ataxia-telangiectasia mutated |
TAIR Aliases | ATATM, ATM, PIG1 |