Genomics
Genome feature
| Region: |
gene
|
Length: |
5346
 |
| Location: | Chr2:16612777-16618122 | ||
Overlapping Features
Genome features that overlap coordinates of this Gene
Proteins
Curated comments from UniProt
| Type | Comment | Proteins |
|---|---|---|
| HOS1_ARATH | function | E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of the transcription factor ICE1. Acts as a negative regulator of cold signaling pathways (PubMed:16702557). Probably involved in recruiting the NUP107-160 subcomplex of the nuclear pore complex to chromatin (Probable). Controls flowering time in response to ambient temperatures (16 and 23 degrees Celsius) and intermittent cold, probably via the regulation of FT and TSF levels (PubMed:22960247). |
| HOS1_ARATH | pathway | Protein modification; protein ubiquitination. |
| HOS1_ARATH | subcellular location | Nuclear after cold treatment. Cytoplasmic when plant are grown or returned to normal growth temperatures. |
| HOS1_ARATH | tissue specificity | Ubiquitously expressed with higher levels in leaf vasculature, roots and root tips. |
Function
Gene Ontology
| cellular component | |
|---|---|
|
nucleus
|
ECO |
|
cytoplasm
|
ECO |
| molecular function | |
|
ubiquitin-protein transferase activity
|
ECO |
|
metal ion binding
|
ECO |
| biological process | |
|
protein ubiquitination
|
ECO |
|
vegetative to reproductive phase transition of meristem
|
ECO |
|
negative regulation of DNA-templated transcription
|
ECO |
|
response to cold
|
ECO |
Interactions
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