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Gene : HOS1 A. thaliana

DB identifier  ? AT2G39810 Secondary Identifier  ? locus:2063917
Name  ? HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1 Brief Description  ubiquitin-protein ligase
TAIR Computational Description  ubiquitin-protein ligase;(source:Araport11)
TAIR Curator Summary  A novel protein with a RING finger motif near the amino terminus. Negative regulator of cold responses. Functions as an E3 ligase required for the ubiquitination of ICE1. HOS1 physically interacts with ICE1 and mediates the ubiquitination of ICE1 both in vitro and in vivo. Overexpression represses the expression of CBFs and their downstream genes and confers increased sensitivity to freezing stress. The mRNA is cell-to-cell mobile.
TAIR Short Description  ubiquitin-protein ligases
TAIR Aliases  ESD6, HOS1

16 Gene Rifs

1 Organism

41 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 5346  
Location: Chr2:16612777-16618122

Gene models - HOS1 AT2G39810

? Gene models

Transcripts: 2  Exons: 21  Introns: 19 

Overlapping Features

? Genome features that overlap coordinates of this Gene

16 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
HOS1_ARATH function E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of the transcription factor ICE1. Acts as a negative regulator of cold signaling pathways (PubMed:16702557). Probably involved in recruiting the NUP107-160 subcomplex of the nuclear pore complex to chromatin (Probable). Controls flowering time in response to ambient temperatures (16 and 23 degrees Celsius) and intermittent cold, probably via the regulation of FT and TSF levels (PubMed:22960247).
HOS1_ARATH pathway Protein modification; protein ubiquitination.
HOS1_ARATH subcellular location Nuclear after cold treatment. Cytoplasmic when plant are grown or returned to normal growth temperatures.
HOS1_ARATH tissue specificity Ubiquitously expressed with higher levels in leaf vasculature, roots and root tips.

2 Proteins

Function

Gene Ontology

cellular component
nucleus  ? ECO  
cytoplasm  ? ECO  
molecular function
ubiquitin-protein transferase activity  ? ECO  
metal ion binding  ? ECO  
biological process
protein ubiquitination  ? ECO  
vegetative to reproductive phase transition of meristem  ? ECO  
negative regulation of DNA-templated transcription  ? ECO  
response to cold  ? ECO  

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets