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Gene : MLO5 A. thaliana

DB identifier  ? AT2G33670 Secondary Identifier  ? locus:2051073
Name  ? MILDEW RESISTANCE LOCUS O 5 Brief Description  Seven transmembrane MLO family protein
TAIR Computational Description  Seven transmembrane MLO family protein;(source:Araport11)
TAIR Curator Summary  A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO5 belongs to the clade III, with AtMLO7, AtMLO8, AtMLO9, and AtMLO10. The gene is expressed during seedling growth, in cotyledon vascular system, and in stigma, anther and pollen grains; it was not expressed in rosette leaves, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). Acts redundantly with MLO9 to tether Ca2+ channels to the pollen tube plasma membrane to effect pollen tube guidance.
TAIR Short Description  Seven transmembrane MLO family protein
TAIR Aliases  ATMLO5, MLO5

1 Gene Rifs

1 Organism

10 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3205  
Location: Chr2:14244951-14248155

Gene models - MLO5 AT2G33670

? Gene models

Transcripts: 1  Exons: 15  Introns: 14 

Overlapping Features

? Genome features that overlap coordinates of this Gene

16 Child Features

1 Cross References

0 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
MLO5_ARATH function May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca(2+)-dependent calmodulin binding and seems not to require heterotrimeric G proteins (By similarity).
MLO5_ARATH similarity Belongs to the MLO family.

1 Proteins

Function

Gene Ontology

cellular component
plasma membrane  ? ECO  
molecular function
calmodulin binding  ? ECO  
biological process
pollen tube guidance  ? ECO  
defense response  ? ECO  
protein localization to plasma membrane  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

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Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets