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Gene : HTH A. thaliana

DB identifier  ? AT1G72970 Secondary Identifier  ? locus:2032627
Name  ? HOTHEAD Brief Description  Glucose-methanol-choline (GMC) oxidoreductase family protein
TAIR Computational Description  Glucose-methanol-choline (GMC) oxidoreductase family protein;(source:Araport11)
TAIR Curator Summary  Originally identified as a mutation that causes floral organs to fuse together. About 10-20% of mutants also have defects in ovules. Mutants have reduced fertility most likely as because of fusions that pistil emergence. The protein has similarity to the mandelonitrile lyase family of FAD containing oxidoreductases and is predicted to be secreted (SignalP).It is expressed in all tissue layers of roots, inflorescences, stems, leaves, and flowers and is also expressed in siliques. Expression is highest in inflorescence and flower tissue.Transmission of mutant alleles to the progeny shows non mendelian segregation- a percentage of mutant alleles revert back to a previous parental (e.g. grandparental) wild type allele. It has been suggested that an RNA template driven or other extra-DNA genomic mechanism may be responsible for the non-mendelian inheritance of HTH. Reversion events in alleles at other loci have also been observed to occur in plants with an hth mutant background indicating a genome wide effect.
TAIR Short Description  Glucose-methanol-choline (GMC) oxidoreductase family protein
TAIR Aliases  EDA17, HTH

2 Gene Rifs

1 Organism

17 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3217  
Location: Chr1:27452748-27455964

Gene models - HTH AT1G72970

? Gene models

Transcripts: 2  Exons: 13  Introns: 11 

Overlapping Features

? Genome features that overlap coordinates of this Gene

11 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
HTH_ARATH function Probable FAD-dependent enzyme. Involved in regulating post-genital organ fusion. Required to limit cellular interactions between contacting epidermal cells during floral development.
HTH_ARATH F4IF15_ARATH similarity Belongs to the GMC oxidoreductase family.
HTH_ARATH tissue specificity Expressed in roots, leaves, stems, inflorescences and siliques. Found not only in epidermis but also in all sub-epidermal cell layers.

2 Proteins

Function

Gene Ontology

cellular component
extracellular region  ? ECO  
molecular function
oxidoreductase activity, acting on CH-OH group of donors  ? ECO  
mandelonitrile lyase activity  ? ECO  
flavin adenine dinucleotide binding  ? ECO  
biological process
fatty acid omega-oxidation  ? ECO  
cell-cell signaling  ? ECO  
embryo sac development  ? ECO  

Interactions

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Expression

eFP Visualization

Data Source: BAR




Co-expression

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Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets