Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
JMJ18_ARATH | function | Histone demethylase that demethylates 'Lys-4' (H3K4me) of histone H3 with a specific activity for H3K4me3 and H3K4me2. No activity on H3K9me3/2, H3K27me3/2 and H3K36me3/2. Involved in the control of flowering time by demethylating H3K4me3 at the FLC locus and repressing its expression. The repression of FLC level and reduction in H3K4me3 at the FLC locus results in induction of the flowering activator FT, which is a downstream target of FLC. |
JMJ18_ARATH | similarity | Belongs to the JARID1 histone demethylase family. |
JMJ18_ARATH | tissue specificity | Expressed in vascular tissues of roots, cotyledons, leaves and flowers (PubMed:22536163). Expressed predominantly in phloem companion cells of roots (PubMed:22536163). Present in inflorescences, roots, siliques, leaves and stems (PubMed:18713399). |
Function
Gene Ontology
cellular component | |
---|---|
nucleus | ECO |
molecular function | |
dioxygenase activity | ECO |
histone H3K4 demethylase activity | ECO |
transcription cis-regulatory region binding | ECO |
metal ion binding | ECO |
biological process | |
regulation of DNA-templated transcription | ECO |
photoperiodism, flowering | ECO |
Interactions
Interaction Network
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