Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
BRO1_ARATH | function | Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. Fusion between endosomes and the vacuole will then target the cargo proteins to the vacuolar lumen (Probable). Associates with FREE1 and ELC to perform function in the ESCRT-I complex. Binds ubiquitin in vitro (PubMed:26902184). Plays a role in the biogenesis of vacuole and multivesicular bodies (MVBs) (PubMed:26324913, PubMed:26342016). Required for the endosomal location of AMSH3 (PubMed:26324913). Mediates high-affinity phosphate transporter trafficking to maintain phosphate homeostasis. Regulates vacuolar degradation of PHT1-1 (PubMed:26342016). |
Function
Gene Ontology
cellular component | |
---|---|
plasmodesma | ECO |
cytosol | ECO |
late endosome | ECO |
multivesicular body | ECO |
cytoplasm | ECO |
molecular function | |
ubiquitin binding | ECO |
biological process | |
endosome to plasma membrane protein transport | ECO |
vacuole organization | ECO |
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | ECO |
multivesicular body organization | ECO |