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Gene : AT1G15130 A. thaliana

DB identifier  ? AT1G15130 Secondary Identifier  ? locus:2037693
Brief Description  Endosomal targeting BRO1-like domain-containing protein
TAIR Computational Description  Endosomal targeting BRO1-like domain-containing protein;(source:Araport11)
TAIR Curator Summary  ALIX mediates endosomal protein trafficking and turnover through the ESCRT/MVB pathway. One target is the phosphate transporter PHT1;1. Modulates ABA-mediated inhibition of plant growth and stomatal aperture (PMID:31363038).
TAIR Short Description  Endosomal targeting BRO1-like domain-containing protein
TAIR Aliases  ALIX

5 Gene Rifs

1 Organism

17 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3978  
Location: Chr1:5206002-5209979 reverse strand

Gene models - AT1G15130 AT1G15130

? Gene models

Transcripts: 1  Exons: 8  Introns: 7 

Overlapping Features

? Genome features that overlap coordinates of this Gene

9 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
BRO1_ARATH function Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. Fusion between endosomes and the vacuole will then target the cargo proteins to the vacuolar lumen (Probable). Associates with FREE1 and ELC to perform function in the ESCRT-I complex. Binds ubiquitin in vitro (PubMed:26902184). Plays a role in the biogenesis of vacuole and multivesicular bodies (MVBs) (PubMed:26324913, PubMed:26342016). Required for the endosomal location of AMSH3 (PubMed:26324913). Mediates high-affinity phosphate transporter trafficking to maintain phosphate homeostasis. Regulates vacuolar degradation of PHT1-1 (PubMed:26342016).

1 Proteins

Function

Interactions

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Expression

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Homology

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0 Homologues

 

Other

9 Data Sets