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Gene : RPS5 A. thaliana

DB identifier  ? AT1G12220 Secondary Identifier  ? locus:2201996
Name  ? RESISTANT TO P. SYRINGAE 5 Brief Description  Disease resistance protein (CC-NBS-LRR class) family
TAIR Computational Description  Disease resistance protein (CC-NBS-LRR class) family;(source:Araport11)
TAIR Curator Summary  Resistance gene, mediates resistance against the bacterial pathogen Pseudomonas syringae. Contains a putative nucleotide binding site composed of kinase-1a (or P-loop), kinase-2a, and putative kinase-3a domains, 13 imperfect leucine-rich repeats, a potential leucine zipper, and two uncharacterized motifs that are well conserved in products of previously isolated R genes. Confers resistance to Pseudomonas syringae strains that express avrPphB.
TAIR Short Description  Disease resistance protein (CC-NBS-LRR class) family
TAIR Aliases  RPS5

8 Gene Rifs

1 Organism

34 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3683  
Location: Chr1:4144257-4147939

Gene models - RPS5 AT1G12220

? Gene models

Transcripts: 3  Exons: 5  Introns: 2 

Overlapping Features

? Genome features that overlap coordinates of this Gene

8 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
RPS5_ARATH function Disease resistance (R) protein that specifically recognizes the avrPphB type III effector avirulence protein from Pseudomonas syringae. Also confers resistance against Hyaloperonospora parasitica (downy mildew). Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Requires PBS1 to trigger the defense reaction against avrPphB. In case of infection by Pseudomonas syringae, AvrPphB triggers RPS5-mediated defense mechanism via the cleavage of PBS1, suggesting that the cleavage of PBS1 could trigger an exchange of ADP for ATP, thereby activating RPS5. May function as a fine-tuned sensor of alterations in the structure of the effector target PBS1.
A0A1P8AW79_ARATH RPS5_ARATH similarity Belongs to the disease resistance NB-LRR family.

2 Proteins

Function

Gene Ontology

cellular component
plasma membrane  ? ECO  
molecular function
ATP binding  ? ECO  
nucleotide binding  ? ECO  
identical protein binding  ? ECO  
signaling receptor activity  ? ECO  
ADP binding  ? ECO  
biological process
defense response  ? ECO  
plant-type hypersensitive response  ? ECO  
defense response to bacterium  ? ECO  
cell death  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets