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Gene : PHOT2 A. thaliana

DB identifier  ? AT5G58140 Secondary Identifier  ? locus:2155821
Name  ? phototropin 2 Brief Description  phototropin 2
TAIR Computational Description  phototropin 2;(source:Araport11)
TAIR Curator Summary  Membrane-bound protein serine/threonine kinase that functions as blue light photoreceptor in redundancy with PHO1. Involved in stomatal opening, chloroplast movement and phototropism. Mediates blue light-induced growth enhancements. PHOT1 and PHOT2 mediate blue light-dependent activation of the plasma membrane H+-ATPase in guard cell protoplasts. PHOT2 possesses two LOV (LOV1 and LOV2, for light-oxygen-voltage-sensing) domains involved in FMN-binding and a C-terminus forming a serine/threonine kinase domain. LOV2 acts as an inhibitor of phototropin kinase in the dark, and light cancels the inhibition through cysteine-FMN adduct formation. LOV1 in contrast acts as an attenuator of photoactivation. Localized to the Golgi apparatus under the induction of blue light. The mRNA is cell-to-cell mobile.
TAIR Short Description  phototropin 2
TAIR Aliases  AtPHOT2, NPL1, PHOT2

43 Gene Rifs

1 Organism

150 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 9287  
Location: Chr5:23523825-23533111

Gene models - PHOT2 AT5G58140

? Gene models

Transcripts: 7  Exons: 155  Introns: 148 

Overlapping Features

? Genome features that overlap coordinates of this Gene

CDSs: 148, Exons: 35, Five Prime UTRs: 10, Gene: 1, mRNAs: 8, Three Prime UTRs: 6

41 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
PHOT2_ARATH-2 PHOT2_ARATH function Protein kinase that acts as a blue light photoreceptor in a signal-transduction pathway for photo-induced movements (PubMed:14739272, PubMed:15821287, PubMed:31904040). Triggers the phosphorylation of AHA1 and AHA2 C-terminal penultimate Thr in guard cells to activate them and induce stomatal opening in response to blue light (BL) (PubMed:15821287, PubMed:31904040). Phosphorylates also BLUS1, a kinase involved in stomatal opening (PubMed:23811955). Mediates calcium spiking of extra- and intracellular origins in response to blue light. Involved in hypocotyl phototropism. Contributes to the chloroplast accumulation in low blue light and mediates their translocation (avoidance response) at high fluence. Regulates stomata opening and photomorphogenesis response of leaf tissue. Not involved in hypocotyl elongation inhibition, anthocyanin accumulation or cotyledon opening.
PHOT2_ARATH-2 A8MS49_ARATH PHOT2_ARATH similarity Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
PHOT2_ARATH-2 PHOT2_ARATH tissue specificity Expressed in leaves, stems and flowers, and to a lower extent in roots (PubMed:11251116). Present in guard cells (at protein level) (PubMed:15821287).

4 Proteins

Function

Gene Ontology

cellular component
Golgi apparatus  ? ECO  
plasma membrane  ? ECO  
membrane  ? ECO  
plastid  ? ECO  
molecular function
ATP binding  ? ECO  
histone H2AS1 kinase activity  ? ECO  
protein serine kinase activity  ? ECO  
identical protein binding  ? ECO  
kinase activity  ? ECO  
protein serine/threonine kinase activity  ? ECO  
FMN binding  ? ECO  
blue light photoreceptor activity  ? ECO  
biological process
protein autophosphorylation  ? ECO  
stomatal movement  ? ECO  
chloroplast relocation  ? ECO  
response to blue light  ? ECO  
circadian rhythm  ? ECO  
phototropism  ? ECO  

Interactions

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets