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Gene : CUL1 A. thaliana

DB identifier  ? AT4G02570 Secondary Identifier  ? locus:2132377
Name  ? cullin 1 Brief Description  cullin 1
TAIR Computational Description  cullin 1;(source:Araport11)
TAIR Curator Summary  Encodes a cullin that is a component of SCF ubiquitin ligase complexes involved in mediating responses to auxin and jasmonic acid. Homozygous auxin-resistant mutants arrest growth soon after germination, lacking a root and hypocotyl. Heterozygotes display a variety of phenotypes consistent with impaired auxin response.
TAIR Short Description  cullin 1
TAIR Aliases  ATCUL1, AXR6, CUL1, ETA1, ICU13

11 Gene Rifs

1 Organism

90 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 5260  
Location: Chr4:1128515-1133774

Gene models - CUL1 AT4G02570

? Gene models

Transcripts: 4  Exons: 83  Introns: 79 

Overlapping Features

? Genome features that overlap coordinates of this Gene

32 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
CUL1_ARATH developmental stage Strong accumulation in embryos (at protein level).
CUL1_ARATH function Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Regulator of mitotic processes which plays a role during gametogenesis and embryogenesis. Together with SKP1, RBX1 and a F-box protein, it forms a SCF complex. The functional specificity of this complex depends of the type of F-box protein. SCF(UFO) is implicated in floral organ development. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling. SCF(ADO1/ZTL), SCF(ADO2/LKP2), SCF(ADO3/FKF1) are related to the circadian clock. SCF(ORE9) seems to be involved in senescence. SCF(EBF1/EBF2) may regulate ethylene signaling.
CUL1_ARATH pathway Protein modification; protein ubiquitination.
CUL1_ARATH similarity Belongs to the cullin family.
CUL1_ARATH subcellular location Mainly nuclear during interphase and preprophase, but also weakly cytoplasmic during interphase. Associated to mitotic spindle during metaphase, and to the phragmoplast during telophase.
CUL1_ARATH tissue specificity Expressed constitutively in roots, seedlings, stems, leaves and flowers.

1 Proteins

Function

Interactions

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Expression

eFP Visualization

Data Source: BAR




Co-expression

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Data Source: ATTED-II
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LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets