Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
CUL1_ARATH | developmental stage | Strong accumulation in embryos (at protein level). |
CUL1_ARATH | function | Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Regulator of mitotic processes which plays a role during gametogenesis and embryogenesis. Together with SKP1, RBX1 and a F-box protein, it forms a SCF complex. The functional specificity of this complex depends of the type of F-box protein. SCF(UFO) is implicated in floral organ development. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling. SCF(ADO1/ZTL), SCF(ADO2/LKP2), SCF(ADO3/FKF1) are related to the circadian clock. SCF(ORE9) seems to be involved in senescence. SCF(EBF1/EBF2) may regulate ethylene signaling. |
CUL1_ARATH | pathway | Protein modification; protein ubiquitination. |
CUL1_ARATH | similarity | Belongs to the cullin family. |
CUL1_ARATH | subcellular location | Mainly nuclear during interphase and preprophase, but also weakly cytoplasmic during interphase. Associated to mitotic spindle during metaphase, and to the phragmoplast during telophase. |
CUL1_ARATH | tissue specificity | Expressed constitutively in roots, seedlings, stems, leaves and flowers. |
Function
Gene Ontology
cellular component | |
---|---|
nucleus | ECO |
condensed nuclear chromosome | ECO |
phragmoplast | ECO |
spindle | ECO |
SCF ubiquitin ligase complex | ECO |
cytoplasm | ECO |
molecular function | |
ubiquitin protein ligase binding | ECO |
biological process | |
protein ubiquitination | ECO |
leaf development | ECO |
regulation of circadian rhythm | ECO |
ubiquitin-dependent protein catabolic process | ECO |
response to auxin | ECO |
ethylene-activated signaling pathway | ECO |
jasmonic acid mediated signaling pathway | ECO |
phloem or xylem histogenesis | ECO |
response to jasmonic acid | ECO |
auxin-activated signaling pathway | ECO |
embryo development ending in seed dormancy | ECO |
SCF complex assembly | ECO |
Interactions
Interaction Network
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