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Gene : AT4G01610 A. thaliana

DB identifier  ? AT4G01610 Secondary Identifier  ? locus:2133402
Brief Description  Cysteine proteinases superfamily protein
TAIR Computational Description  Cysteine proteinases superfamily protein;(source:Araport11)
TAIR Curator Summary  Encodes a capase involved in stress induced cell death. Activity detected in leaf and cell culture.
TAIR Short Description  Cysteine proteinases superfamily protein
TAIR Aliases  AtcathB3

4 Gene Rifs

1 Organism

18 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 2625  
Location: Chr4:694582-697206

Gene models - AT4G01610 AT4G01610

? Gene models

Transcripts: 2  Exons: 21  Introns: 19 

Overlapping Features

? Genome features that overlap coordinates of this Gene

15 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
CATB3_ARATH-2 CATB3_ARATH developmental stage Expressed in developing siliques 13 to 15 days after pollination (DAP). In germinating seeds, expressed from 12 to 48 hours after imbibition with a peak of expression at 24 hours.
CATB3_ARATH-2 CATB3_ARATH function Thiol protease that possesses high activity toward the cathepsin synthetic substrate Arg-Arg-7-amino-4-methylcoumarin (RR-AMC) and the papain substrate Gly-Arg-Arg-AMC (GRR-AMC). Can cleave the papain substrate Phe-Arg-AMC (FR-AMC) and the caspase-3 substrate Asp-Glu-Val-Asp-rhodamine 110 (DEVD-R110). Has no activity towards the caspase-6 substrate VEID-AMC, caspase-8 substrate IETD-AMC and caspase-1 substrate YVAD-AMC (PubMed:27058316). Plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD (PubMed:27058316). Functions redundantly with CATHB1 and CATHB2 in basal defense and distinct forms of plant programmed cell death (PCD). Participates in the establishment of basal resistance against the bacterial pathogen Pseudomonase syringae pv. tomato DC3000. Required for full levels of PCD during resistance (R) gene-mediated hypersensitive response (HR). Involved in the regulation of senescence, a developmental form of PCD in plants (PubMed:19453434). May be involved in the degradation of seed storage proteins during seed germination (PubMed:24600022).
A0A5S9XPB1_ARATH CATB3_ARATH-2 CATB3_ARATH similarity Belongs to the peptidase C1 family.
CATB3_ARATH-2 CATB3_ARATH tissue specificity Expressed in root tips, root vasculature, emerging lateral root, hydathodes, vascular tissue of leaves, vasculature of sepals and anthers, stigma, and vascular bundles at the base and the upper part of the siliques.

3 Proteins

Function

Gene Ontology

cellular component
plant-type vacuole  ? ECO  
secretory vesicle  ? ECO  
molecular function
cysteine-type endopeptidase activity  ? ECO  
biological process
proteolysis  ? ECO  
defense response  ? ECO  
regulation of catalytic activity  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets