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Gene : RGP1 A. thaliana

DB identifier	AT3G02230	Secondary Identifier	locus:2076482
Name	reversibly glycosylated polypeptide 1	Brief Description	reversibly glycosylated polypeptide 1

TAIR Computational Description	reversibly glycosylated polypeptide 1;(source:Araport11)
TAIR Curator Summary	RGP1 is a UDP-arabinose mutase that catalyzes the interconversion between the pyranose and furanose forms of UDP-L-arabinose. It appears to be required for proper cell wall formation. rgp1/rgp2 (at5g15650) double mutants have a male gametophyte lethal phenotype. RGP1 fusion proteins can be found in the cytosol and peripherally associated with the Golgi apparatus. The mRNA is cell-to-cell mobile.
TAIR Short Description	reversibly glycosylated polypeptide 1
TAIR Aliases	ATRGP1, RGP1

2 Gene Rifs

1 Organism

30 Publications

0 Synonyms

Genomics

Genome feature

Region:	gene	Length:	2335
Location:	Chr3:415389-417723

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5 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

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Curated comments from UniProt

Type	Comment	Proteins
RGP1_ARATH	function	UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides. Catalyzes the interconvertion of UDP-L-arabinopyranose (UDP-Arap) and UDP-L-arabinofuranose (UDP-Araf) in vitro. Preferentially catalyzes the formation of UDP-Arap from UDP-Araf. At thermodynamic equilibrium in vitro the ratio of the pyranose form over the furanose form is 95:5. Is not active on other UDP-sugars (UDP-Gal, UDP-Xyl, UDP-Glc, GDP-Man and GDP-Fuc) (PubMed:21478444). Functions redundantly with RGP2 and is essential for proper cell walls and pollen development. Probably involved in the formation of the pectocellulosic cell wall layer intine. Is probably active as heteromer in vivo (PubMed:17071651).
RGP1_ARATH	similarity	Belongs to the RGP family.
RGP1_ARATH	subcellular location	Soluble and associated with peripheral membrane and endomembrane system.
RGP1_ARATH	tissue specificity	Predominantly expressed in shoot and root apical meristems. Expressed in epidermal cells of leaves, inflorescence stems and seed coat. Expressed in pollen.

1 Proteins

Function

Gene Ontology

cellular component
Golgi stack	ECO
plant-type vacuole	ECO
Golgi trans cisterna	ECO
Golgi apparatus	ECO
cytosol	ECO
cytosolic ribosome	ECO
plant-type cell wall	ECO
molecular function
UDP-arabinopyranose mutase activity	ECO
cellulose synthase (UDP-forming) activity	ECO
intramolecular transferase activity	ECO
structural constituent of ribosome	ECO
biological process
pollen development	ECO
plant-type cell wall organization or biogenesis	ECO
cell wall organization	ECO
plant-type cell wall biogenesis	ECO
UDP-L-arabinose metabolic process	ECO

Interactions

Interaction Network

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Expression

Data Source:

BAR Webservices

Querying ATTED Service... Data Source: ATTED-II

Homology

0 Homologues

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9 Data Sets

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