Genomics
Genome feature
| Region: |
gene
|
Length: |
3438
 |
| Location: | Chr1:24589343-24592780 | ||
Overlapping Features Displayer
Proteins
Curated comments from UniProt
| Type | Comment | Proteins |
|---|---|---|
| ORTH5_ARATH | function | E3 ubiquitin-protein ligase. Participates in CpG methylation-dependent transcriptional regulation and epigenetic transcriptional silencing. Mediates ubiquitination with the E2 ubiquitin-conjugating enzyme UBC11. |
| ORTH5_ARATH | pathway | Protein modification; protein ubiquitination. |
| ORTH5_ARATH | subcellular location | Broadly distributed in the nucleus and enriched in the heterochromatic chromocenters. |
| ORTH5_ARATH | tissue specificity | Expressed in inflorescences. |
Function
Gene Ontology
| cellular component | |
|---|---|
|
nucleus
|
ECO |
| molecular function | |
|
methyl-CpNpG binding
|
ECO |
|
histone binding
|
ECO |
|
methyl-CpNpN binding
|
ECO |
|
ubiquitin-protein transferase activity
|
ECO |
|
methyl-CpG binding
|
ECO |
|
metal ion binding
|
ECO |
| biological process | |
|
protein ubiquitination
|
ECO |
|
negative regulation of gene expression via chromosomal CpG island methylation
|
ECO |
Interactions
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