DB identifier | AT1G63990 | Secondary Identifier | locus:2024598 |
Name | sporulation 11-2 | Brief Description | sporulation 11-2 |
TAIR Computational Description | sporulation 11-2;(source:Araport11) |
TAIR Curator Summary | Encodes AtSPO11-2, one of the three Arabidopsis homologues of the archaeal DNA topoisomerase VIA subunit (topo VIA). Required for meiotic recombination. Plants homozygous for atspo11-2 exhibit a severe sterility phenotype. Both male and female meiosis are severely disrupted in the atspo11-2 mutant, and this is associated with severe defects in synapsis during the first meiotic division and reduced meiotic recombination. AtSPO11-1 and AtSPO11-2 have overlapping functions (i.e. both required for meiotic recombination) whereas AtSPO11-3 functions in DNA replication. Required for double-strand break induction. |
TAIR Short Description | sporulation 11-2 |
TAIR Aliases | SPO11-2 |