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GO Term : GO:0097071 interferon regulatory factor complex GO

Namespace  cellular_component Obsolete  false
Description  A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit.

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1 Ontology

Trail: GOTerm

0 Ontology Annotations

3 Parents

Trail: GOTerm

7 Relations

Trail: GOTerm

1 Synonyms

Trail: GOTerm