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GO Term : GO:0061290 canonical Wnt signaling pathway involved in metanephric kidney development GO

Namespace  biological_process Obsolete  false
Description  The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.

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1 Ontology

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29 Parents

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38 Relations

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3 Synonyms

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