help  | faq  | software  | BAR

GO Term : GO:0039530 MDA-5 signaling pathway GO

Namespace  biological_process Obsolete  false
Description  The series of molecular signals initiated by the binding of dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1). MDA-5 detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines.

0 Cross References

0 Data Sets

1 Ontology

Trail: GOTerm

0 Ontology Annotations

46 Parents

Trail: GOTerm

71 Relations

Trail: GOTerm

4 Synonyms

Trail: GOTerm