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GO Term : GO:0060070 canonical Wnt signaling pathway GO

Namespace  biological_process Obsolete  false
Description  The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.

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1 Ontology

Trail: GOTerm

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16 Parents

Trail: GOTerm

89 Relations

Trail: GOTerm

6 Synonyms

Trail: GOTerm