DB identifier | AT5G15170 | Secondary Identifier | locus:2150931 |
Name | tyrosyl-DNA phosphodiesterase 1 | Brief Description | tyrosyl-DNA phosphodiesterase-like protein |
TAIR Computational Description | tyrosyl-DNA phosphodiesterase-like protein;(source:Araport11) |
TAIR Curator Summary | Tyrosyl-DNA phosphodiesterase 1 involved in DNA repair. TDP1 is involved the repair of Topoisomerase 1 cleavage complexes (tdp1 mutants are camptotecin hypersensitive). tdp1/wss1A double mutants show a synergistic sensitivity after camptothecin treatment. tdp1/mus81 double mutants show an elevated number of dead cells in root meristems after camptothecin treatment (compared to the single mutants). |
TAIR Short Description | tyrosyl-DNA phosphodiesterase-related |
TAIR Aliases | TDP1 |