Description | This entry represents a group of proteins from animals, including AP-4 complex accessory subunit RUSC1/2.RUSC1, also called RUN and SH3 domain-containing protein 1, may acts as a signalling adapter that translocates to the nuclear envelope and regulates neurotrophin-induced neurite outgrowth [ , , , , ].RUSC2, also called RUN and SH3 domain-containing protein 2, is a novel interacting molecule for the active GTP-bound conformation of Rab1. It may function as a link between the targeting of endoplasmic reticulum derived vesicles, triggered by the Rab1 GTPase and a signaling pathway regulated by molecules containing SH3 and/or poly-proline regions [, , , ]. | Name | AP-4 complex accessory subunit RUSC1/2 |
Short Name | RUSC1_2 | Type | Family |