Description | F-box only protein 38 (FBX38) is an E3 ubiquitin ligase that mediates Lys48-linked poly-ubiquitination and subsequent proteasome degradation of PD-1, an immune checkpoint mediator and negative regulator of T cell-mediated immunity [ ]. | Name | F-box only protein 38 |
Short Name | FBX38 | Type | Family |