Description | Pellino proteins are E3 ubiquitin ligases that play an important role in immunity [ , ]. Pellinos contain a CHC2CHC2 RING E3 ubiquitin ligase domain []. Mammalian Pellinos have been shown to mediate polyubiquitination of interleukin-1 receptor-associated kinase (IRAK) [, ]. | Name | Pellino family |
Short Name | Pellino_fam | Type | Family |