| Description | This family represents protein spackle from Bacteriophage T4, which inhibits viral DNA ejection into the host cytoplasm, thereby conferring the infected host bacteria with immunity against secondary phage infection [ ]. It localizes to the periplasm and inhibits the activity of tail-associated lysozyme, thereby preventing penetration by the tail tube of incoming phages [, ]. It interacts with the baseplate central spike protein gp5, therefore, spackle selectively inhibits the lysozyme activity of gp5, but not that of T4 lysozyme. | Name | Protein spackle |
| Short Name | SPACKLE_T4 | Type | Family |
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