| Description | The ESAT-6/WXG100 superfamily includes proteins that are secreted in a full-length form and adopt a four-helix bundle structure [ ]. They represent the prototypical substrates of bacterial type VII secretion systems []. The best characterized member of the superfamily is ESAT-6, a small protein that appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. Homologues have been detected in other Gram-positive bacterial species []. | Name | ESAT-6-like superfamily |
| Short Name | ESAT-6-like_sf | Type | Homologous_superfamily |
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