Description | This entry includes PglZ, an alkaline phosphatase-like protein associated with BREX (bacteriophage exclusion) type 1 systems [ ]. This system provides immunity against bacteriophage, it allows phage adsorption but blocks phage DNA replication. PglZ is predicted to have a phosphatase activity and is described as probable antitoxin component of a type II toxin-antitoxin (TA) system, that inhibits the toxic activity of its cognate toxin PglX []. PglZ is one of the four genes (pglW, pglX, pglY, and pglZ) that were shown to be necessary and sufficient for the Pgl phenotype []. | Name | BREX system phosphatase PglZ |
Short Name | BREX_PglZ | Type | Family |