Description | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, a bacterial ispD protein, catalyzes the third step of the deoxyxylulose-5-phosphate pathway (DXP) of isoprenoid biosynthesis; the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol 4-phosphate [ ]. The isoprenoid pathway is a well known target for anti-infective drug development [, ].This entry represents a pattern that identifies IspD. The pattern is centred on a central conserved region that contains a conserved Asp and Arg residues. | Name | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site |
Short Name | ISPD_synthase_CS | Type | Conserved_site |