| Description | This group contains response regulators involved in the control of heterocyst pattern formation. Heterocysts are microaerobic, N 2-fixing cells that form in a patterned array within O 2-producing filamentous cyanobacteria [ ]. PatA plays a role in controlling the differentiation process that produces heterocysts [, , ]. PatA and HetR are believed to be components of the same environment-sensing regulatory circuit in species ofAnabaena[ , , ].Response regulators of the microbial two-component signal transduction systems typically consist of an N-terminal CheY-like receiver (phosphoacceptor) domain and a C-terminal output (usually DNA-binding) domain. Members of this group, however, have the receiver domain in the C-terminal region, and the exact function of the N-terminal domain is not clear yet. In two-component signal transduction systems, in response to an environmental stimulus, a phosphoryl group is transferred from the His residue of sensor histidine kinase to an Asp residue in the CheY-like receiver domain of the cognate response regulator [ , , ]. Phosphorylation of the receiver domain induces conformational changes that activate an associated output domain, which in turn triggers the response. Phosphorylation-induced conformational changes in response regulator molecules have been demonstrated in direct structural studies []. | Name | Signal transduction response regulator, heterocyst pattern formation, PatA |
| Short Name | Sig_transdc_resp-reg_PatA | Type | Family |
Powered by
Have you tried our InterMine mobile apps?
and interoperation is funded by 
