| Description | This entry represents a domain found in proteobacteria, including the type VI secretion system (T6SS) immunity protein TsiT from Pseudomonas aeruginosa ( ), which belongs to the Imm52 family. This protein can suppress the virulence of TseT [ ]. TsiT adopts a β-sandwich fold with nine α-helices and an eight-stranded antiparallel central β-sheet. It has a large electro-negative pocket with hydrophobic surroundings that play a role in the interaction with TseT [, ]. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbour of the toxin gene, usually containing a domain of the Tox-REase-5 family []. | Name | Immunity protein 52 |
| Short Name | Imm52 | Type | Domain |
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