Description | This entry represents a family of proteins specific to beta and gamma proteobacteria, including the type VI secretion system (T6SS) immunity protein TsiT from Pseudomonas aeruginosa ( ), which belongs to the Imm52 family. This protein can suppress the virulence of TseT [ ]. TsiT adopts a β-sandwich fold with nine α-helices and an eight-stranded antiparallel central β-sheet. It has a large electro-negative pocket with hydrophobic surroundings that play a role in the interaction with TseT [, ]. | Name | Imm52 family, TsiT-like |
Short Name | TsiT-like | Type | Family |