| Description | Interleukins are a group of cytokines that have important roles in cell growth, differentiation, and motility, and in the functioning of the immune system.Interleukin-12 (also known as natural killer cell stimulatory factor, and cytotoxic lymphocyte maturation factor) is a 75kDa heterodimer composed of two genetically unrelated subunits - an alpha chain (p35 subunit) and a beta chain (p40 subunit). Production of the cytokine plays an important role in the generation of cell-mediated immunity against many infectious pathogens [ ]. The interluekin-12 beta chain also associates with interleukin-23 alpha to form interleukin-23 [], a proinflammatory cytokine that is overexpressed in and around tumour tissues, where it induces local inflammation and promotes tumour development [].This entry represents Interleukin-12 beta. | Name | Interleukin-12 beta |
| Short Name | IL-12_beta | Type | Family |
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