Description | This is the C-terminal domain of RNF31 (also known as HOIP) from humans. HOIP is a component of the linear ubiquitin chain assembly complex (LUBAC), which synthesizes the linear ubiquitin chains that help control innate immunity and inflammation [ , , ]. This region has an RBR domain which catalyzes the transfer of ubiquitin onto a substrate[ ]. | Name | RNF31, C-terminal |
Short Name | RNF31_C | Type | Domain |