Description | Interleukins (IL) are a group of cytokines that play an important role in the immune system. They modulate inflammation and immunity by regulating growth, mobility and differentiation of lymphoid and other cells.Interleukin-16 (IL-16, also known as lymphocyte chemoattractant factor) is a proinflammatory cytokine that signals via CD4, inducing chemotactic and immunomodulatory responses of CD4+ lymphocytes, monocytes and eosinophils [ ]. The cytokine has been implicated in the exacerbation of a number of infectious, immune-mediated and autoimmune inflammatory disorders, including atopic dermatitis, irritable bowel syndrome, systemic lupus erythematosus, neurodegenerative disorders, and viral infections [].This entry represents interleukin-16. | Name | Interleukin-16 |
Short Name | IL-16 | Type | Family |