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Protein Domain : IPR019743

Description  Involucrin [ , ] is a highly reactive, soluble, transglutaminase substrate protein present in keratinocytes of epidermis and other stratified squamous epithelia. Involucrin first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase thus helping in the formation of an insoluble envelope beneath the plasma membrane [] functioning as a glutamyl donor during assembly of the cornified envelope.This entry represents the signature pattern for involucrin, which is located at the N-terminal extremity of these proteins. Name  Involucrin, conserved site
Short Name  Involucrin_CS Type  Conserved_site
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3 Publications

Genomics

1 Cross References

 

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1 Data Sets

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0 Protein Domain Regions