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Search results 2401 to 2500 out of 2746 for Pattern triggered immunity

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Type Details Score
GO Term
GO:0039530 | MDA-5 signaling pathway
Description: The series of molecular signals initiated by the binding of dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1). MDA-5 detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines.
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Protein Domain
IPR010069
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Protein Domain
IPR046872
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Protein Domain
IPR042151
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Protein Domain
IPR037883
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: we report the characterization of bHLH84, which funtions as a transcriptional activator that enhances the autoimmunity of NLR mutant snc1 (suppressor of npr1-1, constitutive 1) and confers enhanced immunity in wild-type backgrounds when overexpressed
Organism: A. thaliana
Gene: AT2G14760
PubMed Id: 25144198
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: The induction of defence responses and disease resistance to X. campestris pv. campestris strain 8004 requires NDR1 , RAR1 and SGT1b, suggesting that effector-triggered immunity plays a large role in resistance to this strain.
Organism: A. thaliana
Gene: NDR1
PubMed Id: 21029323
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: The induction of defence responses and disease resistance to X. campestris pv. campestris strain 8004 requires NDR1 , RAR1 and SGT1b, suggesting that effector-triggered immunity plays a large role in resistance to this strain.
Organism: A. thaliana
Gene: SGT1B
PubMed Id: 21029323
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: The induction of defence responses and disease resistance to X. campestris pv. campestris strain 8004 requires NDR1 , RAR1 and SGT1b, suggesting that effector-triggered immunity plays a large role in resistance to this strain.
Organism: A. thaliana
Gene: PBS2
PubMed Id: 21029323
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: This study found that the expression of YSL3 was induced by salicylic acid in an NONEXPRESSOR OF PR1 (NPR1)-dependent pathway and a biological role of YSL3 in the innate immunity of plants was illuminated.
Organism: A. thaliana
Gene: YSL3
PubMed Id: 24845074
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: The role of EDM2 in plant immunity is limited and does not include a function in basal defense. EDM2 acts upstream of the floral repressor FLC and downstream of WNK8 to affect floral transition.
Organism: A. thaliana
Gene: EDM2
PubMed Id: 20149132
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Protein Domain
IPR016379
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Protein Domain
IPR005415
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Protein Domain
IPR043427
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Protein Domain
IPR003537
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Protein Domain
IPR034525
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Protein Domain
IPR006182
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: The results revealed clear differences in the MIR168 promoter sequence of monocot and dicot plant species. Moreover, the pattern of MIR168 promoter expression differed between monocots and dicots. These results suggest that, unlike that of miR168, the MIR168 promoter is not conserved in monocots and dicots.
Organism: A. thaliana
Gene: MIR168B
PubMed Id: 27323093
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GO Term
GO:0021908 | retinoic acid receptor signaling pathway involved in spinal cord anterior/posterior pattern formation
Description: The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.
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Publication
24920804
First Author: Dulek DE
Title: STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.
Year: 2014
Journal: J Virol
Volume: 88
Pages: 9655-72
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Protein Domain
IPR002211
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Protein Domain
IPR033881
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Protein Domain
IPR022319
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Protein Domain
IPR009229
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Protein Domain
IPR000869
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Protein Domain
IPR007111
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Protein Domain
IPR022776
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Protein Domain
IPR019818
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Protein Domain
IPR019805
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Protein Domain
IPR019801
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Protein Domain
IPR020867
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Protein Domain
IPR039005
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Protein Domain
IPR013111
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Protein Domain
IPR008254
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Protein Domain
IPR047942
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Protein Domain
IPR047943
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Protein Domain
IPR000545
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Protein Domain
IPR011043
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Protein Domain
IPR045869
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Protein Domain
IPR013141
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GO Term
GO:0035882 | defecation rhythm
Description: The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated.
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GO Term
GO:0039557 | suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity
Description: Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). IRF7 a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.
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GO Term
GO:0060108 | annular furrow extracellular matrix
Description: The extracellular matrix part that is a regularly spaced indentation in the outer cortical layer of the cuticle. The pattern of annular furrows corresponds to sites of invaginations in hypodermal cell membranes that, in turn, correspond to submembranous regions where actin microfilament bundles assemble early in lethargus, the first phase of the molting cycle in which activity and feeding decline.
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: used natural variation in Arabidopsis thaliana to study the role of zinc in regulating growth. We identify allelic variation of the systemic immunity gene AZI1 as a key for determining root growth responses to low zinc conditions
Organism: A. thaliana
Gene: AZI1
PubMed Id: 29608565
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Protein Domain
IPR031922
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Protein Domain
IPR030385
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Protein Domain
IPR046444
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Protein Domain
IPR025136
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Protein Domain
IPR009105
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Protein Domain
IPR036725
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Interaction Term
MI:0602 | chemical footprinting
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Interaction Term
MI:0605 | enzymatic footprinting
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GO Term
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Description: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: Overexpression and repression of miR393 respectively suppressed and induced transcripts of the lectin receptor-like kinases genes. The results indicate that miR393 regulates three lectin receptor-like kinases following perception of bacterial Lipopolysaccharide, in support of immunity and basal resistance.
Organism: A. thaliana
Gene: MIR393A
PubMed Id: 30940349
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: Overexpression and repression of miR393 respectively suppressed and induced transcripts of the lectin receptor-like kinases genes. The results indicate that miR393 regulates three lectin receptor-like kinases following perception of bacterial Lipopolysaccharide, in support of immunity and basal resistance.
Organism: A. thaliana
Gene: MIR393B
PubMed Id: 30940349
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: AtBMI1C is an imprinted gene expressed from the maternal allele in the endosperm but biallelically expressed in stamen. It was found that the characteristic expression pattern of AtBMI1C is the result of a complex epigenetic regulation that involves CG DNA methylation, RNA-directed non-CG DNA methylation (RdDM), and PcG activity. [BMI1C]
Organism: A. thaliana
Gene: AT3G23060
PubMed Id: 21914649
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GO Term
GO:0021907 | fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation
Description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.
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Protein Domain
IPR020046
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Protein Domain
IPR044063
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Protein Domain
IPR003932
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Protein Domain
IPR004333
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Protein Domain
IPR030397
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Protein Domain
IPR000966
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Protein Domain
IPR022332
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Protein Domain
IPR022379
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Protein Domain
IPR000870
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Protein Domain
IPR036893
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Protein Domain
IPR020563
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Protein Domain
IPR020596
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Protein Domain
IPR019829
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Protein Domain
IPR019825
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Protein Domain
IPR020904
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Protein Domain
IPR003651
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Protein Domain
IPR013425
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Protein Domain
IPR012259
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Protein Domain
IPR001796
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Protein Domain
IPR018085
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Ontology Term
- | Fusion of virus membrane with host membrane
Description: Viral protein involved in the merging of the virion membrane with a host membrane during viral penetration into host cell. Viral fusion proteins drive this fusion reaction by undergoing a major conformational change that is triggered by interactions with the target cell. The specific trigger depends on the virus and can be exposure to low pH in the endocytic pathway or interaction of the virion with the host receptor(s). In prokaryotic viruses, host-virus membrane fusion can occur either at the host outer membrane or plasma membrane. Bacteriophages such as cystoviridae fuse their external envelope with the host outer membrane, whereas others like tectiviridae fuse their inner envelope with the host plasma membrane
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Protein Domain
IPR031719
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Protein Domain
IPR034526
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Protein Domain
IPR003546
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Protein Domain
IPR000690
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: ARR2 directly activates the expression of PRX33 and PRX34, which are required for SA- and PAMP-triggered ROS production. Thus, the CK signaling pathway regulates ROS homeostasis in guard cells, which leads to enhanced stomatal immunity and plant resistance to bacteria.
Organism: A. thaliana
Gene: PRXCA
PubMed Id: 28254779
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: ARR2 directly activates the expression of PRX33 and PRX34, which are required for SA- and PAMP-triggered ROS production. Thus, the CK signaling pathway regulates ROS homeostasis in guard cells, which leads to enhanced stomatal immunity and plant resistance to bacteria.
Organism: A. thaliana
Gene: PRXCB
PubMed Id: 28254779
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: ARR2 directly activates the expression of PRX33 and PRX34, which are required for SA- and PAMP-triggered ROS production. Thus, the CK signaling pathway regulates ROS homeostasis in guard cells, which leads to enhanced stomatal immunity and plant resistance to bacteria.
Organism: A. thaliana
Gene: RR2
PubMed Id: 28254779
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Protein Domain
IPR018769
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Protein Domain
IPR043969
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Protein Domain
IPR046445
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Protein Domain
IPR018542
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Protein Domain
IPR000798
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Protein Domain
IPR011174
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Protein Domain
IPR021774
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UniProt Feature
UniProt Feature
Begin: 377
Description: Abolishes PCRK1 function in pattern-triggered immunity (PTI); when associated with A-373 and A-385.
Type: mutagenesis site
End: 377
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UniProt Feature
UniProt Feature
Begin: 385
Description: Abolishes PCRK1 function in pattern-triggered immunity (PTI); when associated with A-373 and A-377.
Type: mutagenesis site
End: 385
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UniProt Feature
UniProt Feature
Begin: 373
Description: Abolishes PCRK1 function in pattern-triggered immunity (PTI); when associated with A-377 and A-385.
Type: mutagenesis site
End: 373
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GO Term
GO:0039548 | suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity
Description: Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.
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Protein Domain
IPR026210
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Protein Domain
IPR001374
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Protein Domain
IPR004036
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Protein Domain
IPR004035
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