help  | faq  | software  | BAR

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, pathways, authors, ontology terms, etc. (e.g. eve, embryo, zen, allele)
  • Use OR to search for either of two terms (e.g. fly OR drosophila) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. dros* for partial matches or fly AND NOT embryo to exclude a term

Search results 701 to 800 out of 1098 for Microbe-associated molecular pattern

Category restricted to GOTerm (x)

<< First    < Previous  |  Next >    Last >>
0.07s

Categories

Category: GOTerm
« show all
Type Details Score
GO Term
GO:0003155 | BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry
Description: The series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that contributes to the determination of lateral mesoderm left/right asymmetry.
•
•
•
•
•
GO Term
GO:0035567 | non-canonical Wnt signaling pathway
Description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin.
•
•
•
•
•
GO Term
GO:0007214 | gamma-aminobutyric acid signaling pathway
Description: The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell.
•
•
•
•
•
GO Term
GO:0007604 | phototransduction, UV
Description: The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers.
•
•
•
•
•
GO Term
GO:0048008 | platelet-derived growth factor receptor signaling pathway
Description: The series of molecular signals initiated by a ligand binding to a platelet-derived growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0031929 | TOR signaling
Description: The series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.
•
•
•
•
•
GO Term
GO:0038130 | ERBB4 signaling pathway
Description: The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4 on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038146 | chemokine (C-X-C motif) ligand 12 signaling pathway
Description: The series of molecular signals initiated by the binding of the chemokine CXCL12 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0048009 | insulin-like growth factor receptor signaling pathway
Description: The series of molecular signals initiated by a ligand binding to an insulin-like growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0044348 | plant-type cell wall cellulose catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall.
•
•
•
•
•
GO Term
GO:0052541 | plant-type cell wall cellulose metabolic process
Description: The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.
•
•
•
•
•
GO Term
GO:0046535 | detection of chemical stimulus involved in sensory perception of umami taste
Description: The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates.
•
•
•
•
•
GO Term
GO:0060797 | transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment
Description: The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, which contributes to an unspecified cell adopting a mesoderm fate.
•
•
•
•
•
GO Term
GO:0061057 | peptidoglycan recognition protein signaling pathway
Description: The series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.
•
•
•
•
•
GO Term
GO:0071893 | BMP signaling pathway involved in nephric duct formation
Description: The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to nephric duct formation.
•
•
•
•
•
GO Term
GO:0086023 | adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
Description: The series of molecular signals beginning with a G protein-coupled adrenergic cell surface receptor combining with epinephrine or norepinephrine, to activate adenylate cyclase, which contributes to a circulatory system process carried out by the heart.
•
•
•
•
•
GO Term
GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
Description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade.
•
•
•
•
•
GO Term
GO:0090244 | Wnt signaling pathway involved in somitogenesis
Description: The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis.
•
•
•
•
•
GO Term
GO:0098509 | sensory perception of humidity
Description: The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.
•
•
•
•
•
GO Term
GO:0140057 | vacuole-mitochondria membrane tethering
Description: The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.
•
•
•
•
•
GO Term
GO:2000699 | fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
Description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.
•
•
•
•
•
GO Term
GO:0016708 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
Description: Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.
•
•
•
•
•
GO Term
GO:0140657 | ATP-dependent activity
Description: A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.
•
•
•
•
•
GO Term
GO:0051403 | stress-activated MAPK cascade
Description: The series of molecular signals in which a stress-activated MAP kinase cascade relays a signal; MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase.
•
•
•
•
•
GO Term
GO:0032005 | signal transduction involved in positive regulation of conjugation with cellular fusion
Description: The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.
•
•
•
•
•
GO Term
GO:0007173 | epidermal growth factor receptor signaling pathway
Description: The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0009589 | detection of UV
Description: The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
•
•
•
•
•
GO Term
GO:0008293 | torso signaling pathway
Description: The series of molecular signals initiated by an extracellular ligand binding to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0048017 | inositol lipid-mediated signaling
Description: The series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids.
•
•
•
•
•
GO Term
GO:0048861 | leukemia inhibitory factor signaling pathway
Description: The series of molecular signals initiated by the binding of a leukemia inhibitory factor to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0099602 | neurotransmitter receptor regulator activity
Description: A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing.
•
•
•
•
•
GO Term
GO:0035385 | Roundabout signaling pathway
Description: The series of molecular signals initiated by a SLIT protein binding to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway
Description: The series of molecular signals initiated a ligand binding to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038026 | reelin-mediated signaling pathway
Description: The series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038115 | chemokine (C-C motif) ligand 19 signaling pathway
Description: The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038116 | chemokine (C-C motif) ligand 21 signaling pathway
Description: The series of molecular signals initiated by the binding of the C-C chemokine CCL21 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038148 | chemokine (C-C motif) ligand 2 signaling pathway
Description: The series of molecular signals initiated by the binding of the C-C chemokine CCL2 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038161 | prolactin signaling pathway
Description: The series of molecular signals initiated by the binding of the peptide hormone prolactin to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038190 | VEGF-activated neuropilin signaling pathway
Description: The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a neuropilin protein on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0060902 | regulation of hair cycle by BMP signaling pathway
Description: The series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that modulates the rate, frequency or extent of the hair cycle.
•
•
•
•
•
GO Term
GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway
Description: The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing (NOD) protein receptor, and ending with regulation of a downstream cellular process.
•
•
•
•
•
GO Term
GO:0110135 | Norrin signaling pathway
Description: The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state.
•
•
•
•
•
GO Term
GO:2000701 | glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
Description: The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.
•
•
•
•
•
GO Term
GO:0000160 | phosphorelay signal transduction system
Description: A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
•
•
•
•
•
GO Term
GO:0015267 | channel activity
Description: Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
•
•
•
•
•
GO Term
GO:0003306 | Wnt signaling pathway involved in heart development
Description: The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.
•
•
•
•
•
GO Term
GO:0003154 | BMP signaling pathway involved in determination of left/right symmetry
Description: The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the determination of left/right symmetry.
•
•
•
•
•
GO Term
GO:0007179 | transforming growth factor beta receptor signaling pathway
Description: The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0003303 | BMP signaling pathway involved in heart jogging
Description: The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the process of heart jogging.
•
•
•
•
•
GO Term
GO:0009585 | red, far-red light phototransduction
Description: The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.
•
•
•
•
•
GO Term
GO:0048010 | vascular endothelial growth factor receptor signaling pathway
Description: The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor (VEGFR) on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0036323 | vascular endothelial growth factor receptor-1 signaling pathway
Description: The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-1 (VEGFR-1) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway
Description: The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-2 (VEGFR-2) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0036325 | vascular endothelial growth factor receptor-3 signaling pathway
Description: The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-3 (VEGFR-3) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway
Description: The series of molecular signals initiated by a ligand binding of a heterodimeric TLR1:TLR2 complex, followed by transmission of the signal by the activated receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway
Description: The series of molecular signals initiated by a ligand binding of a heterodimeric TLR6:TLR2 complex, followed by transmission of the signal by the activated receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0051931 | regulation of sensory perception
Description: Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.
•
•
•
•
•
GO Term
GO:0045500 | sevenless signaling pathway
Description: The series of molecular signals initiated by an extracellular ligand binding to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0060227 | Notch signaling pathway involved in camera-type eye photoreceptor fate commitment
Description: The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate.
•
•
•
•
•
GO Term
GO:0060242 | contact inhibition
Description: The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation.
•
•
•
•
•
GO Term
GO:0060853 | Notch signaling pathway involved in arterial endothelial cell fate commitment
Description: The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.
•
•
•
•
•
GO Term
GO:0060869 | transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission
Description: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission.
•
•
•
•
•
GO Term
GO:0061289 | Wnt signaling pathway involved in kidney development
Description: The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time.
•
•
•
•
•
GO Term
GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway
Description: The series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway
Description: The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 1 (NOD1) protein receptor, and ending with regulation of a downstream cellular process.
•
•
•
•
•
GO Term
GO:0070431 | nucleotide-binding oligomerization domain containing 2 signaling pathway
Description: The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 2 (NOD2) protein receptor, and ending with regulation of a downstream cellular process.
•
•
•
•
•
GO Term
GO:1990408 | calcitonin gene-related peptide receptor signaling pathway
Description: The series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers.
•
•
•
•
•
GO Term
GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Description: Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
•
•
•
•
•
GO Term
GO:0002079 | inner acrosomal membrane
Description: The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.
•
•
•
•
•
GO Term
GO:0007199 | G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
Description: The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP).
•
•
•
•
•
GO Term
GO:0021774 | retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification
Description: The series of molecular signals initiated by binding of a ligand to a retinoic acid receptor in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.
•
•
•
•
•
GO Term
GO:0021775 | smoothened signaling pathway involved in ventral spinal cord interneuron specification
Description: The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.
•
•
•
•
•
GO Term
GO:0031500 | Tea1 cell-end complex
Description: A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.
•
•
•
•
•
GO Term
GO:0035471 | luteinizing hormone signaling pathway involved in ovarian follicle development
Description: The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure.
•
•
•
•
•
GO Term
GO:0035480 | regulation of Notch signaling pathway involved in heart induction
Description: Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.
•
•
•
•
•
GO Term
GO:0035604 | fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
Description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.
•
•
•
•
•
GO Term
GO:0035660 | MyD88-dependent toll-like receptor 4 signaling pathway
Description: The series of molecular signals initiated by a ligand binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
•
•
•
•
•
GO Term
GO:0038033 | positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
Description: The series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to its receptor on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis.
•
•
•
•
•
GO Term
GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway
Description: The series of molecular signals initiated by collagen binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038086 | VEGF-activated platelet-derived growth factor receptor signaling pathway
Description: The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038091 | positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
Description: The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of cell proliferation.
•
•
•
•
•
GO Term
GO:0038145 | macrophage colony-stimulating factor signaling pathway
Description: The series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0048011 | neurotrophin TRK receptor signaling pathway
Description: The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0060799 | transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification
Description: The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate.
•
•
•
•
•
GO Term
GO:0060851 | vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment
Description: The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate.
•
•
•
•
•
GO Term
GO:0061151 | BMP signaling pathway involved in renal system segmentation
Description: The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to the segmentation of the renal system.
•
•
•
•
•
GO Term
GO:1900164 | nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
Description: The series of molecular signals initiated by a nodal protein binding to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.
•
•
•
•
•
GO Term
GO:0098581 | detection of external biotic stimulus
Description: The series of events in which an external biotic stimulus is detected and converted into a molecular signal. An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated.
•
•
•
•
•
GO Term
GO:0061312 | BMP signaling pathway involved in heart development
Description: The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to the progression of the heart over time.
•
•
•
•
•
GO Term
GO:0003402 | planar cell polarity pathway involved in axis elongation
Description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal to modulate cytoskeletal elements and control cell polarity that contributes to axis elongation.
•
•
•
•
•
GO Term
GO:0003711 | transcription elongation factor activity
Description: A molecular function that stimulates the elongation properties of the RNA polymerase during the elongation phase of transcription. A subclass of transcription elongation factors enable the transition from transcription initiation to elongation, while another class rescue stalled RNA polymerases.
•
•
•
•
•
GO Term
GO:0007205 | protein kinase C-activating G protein-coupled receptor signaling pathway
Description: The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
•
•
•
•
•
GO Term
GO:0007223 | Wnt signaling pathway, calcium modulating pathway
Description: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
•
•
•
•
•
GO Term
GO:0009754 | detection of jasmonic acid stimulus
Description: The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule.
•
•
•
•
•
GO Term
GO:0021881 | Wnt-activated signaling pathway involved in forebrain neuron fate commitment
Description: The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain.
•
•
•
•
•
GO Term
GO:0035791 | platelet-derived growth factor receptor-beta signaling pathway
Description: The series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038087 | VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway
Description: The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to an alpha-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038088 | VEGF-activated platelet-derived growth factor receptor-beta signaling pathway
Description: The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a beta-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038118 | C-C chemokine receptor CCR7 signaling pathway
Description: The series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•
GO Term
GO:0038159 | C-X-C chemokine receptor CXCR4 signaling pathway
Description: The series of molecular signals initiated by a the C-X-C chemokine type 4 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.
•
•
•
•
•





BAR logo CAGEF logo CAGEF logo Araport logo JCVI logo TACC logo

InterMine is funded by the and interoperation is funded by

© 2002 - 2021 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom