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Search results 1 to 14 out of 14 for Microbe-associated molecular pattern

Category restricted to OntologyTerm (x)

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Category: OntologyTerm
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Type Details Score
Ontology Term
- | Coiled coil
Description: Protein which contains at least one coiled coil domain, a type of secondary structure composed of two or more alpha helices which entwine to form a cable structure. In proteins, the helical cables serve a mechanical role in forming stiff bundles of fibres
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Ontology Term
- | Innate immunity
Description: Protein involved in innate immunity, an inborn defense mechanism used by organisms to defend themselves against invasion by pathogens (bacteria, fungi, viruses, etc.). Initially discovered in insects which are devoid of an adaptive immune system and rely only on innate immune reactions for their defense, this immediate response accomplishes many activities including recognition and effector functions. Recognition is mediated by broad specificity, pattern recognition, receptors which recognize many related molecular structures (e.g. polysaccharides, polynucleotides) present in microorganisms but not found in the host. The innate responses include the release of antimicrobial peptides, production of cytokines, acute- phase proteins, complement. Although many different innate immune mechanisms are deployed for host defence, a unifying theme of innate immunity is the use of germline-encoded pattern recognition receptors for pathogens or damaged self components, such as the Toll-like receptors, nucleotide-binding domain leucine-rich repeat (LRR)- containing receptors, retinoic acid-inducible gene I-like RNA helicases and C-type lectin receptors
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Ontology Term
- | Dioxygenase
Description: Enzyme that reduces molecular oxygen by incorporating both atoms into its substrate(s)
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Ontology Term
- | Biological rhythms
Description: Protein involved in the generation of rhythmic pattern of behaviors or activities, e.g. circadian rhythm which is a metabolic or behavioural rhythm within a cycle of 24 hours
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Ontology Term
- | Monooxygenase
Description: Enzymes that reduce molecular oxygen by incorporating one oxygen atom into its substrate and the other one in water
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Ontology Term
- | Segmentation polarity protein
Description: Protein involved in the division of the embryo into segments and which is responsible for determining the internal polarity of the segments Segment polarity gene mutations are lethal and change the pattern and, often the polarity, of every segment
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Ontology Term
- | Brugada syndrome
Description: Protein which, if defective, causes Brugada syndrome, a heart disease characterized by an electrocardiogram pattern showing ST segment elevation in right precordial leads (V1 to V3), incomplete or complete right bundle branch block, and ventricular tachyarrhythmia. In some cases, tachycardia does not terminate spontaneously and it may degenerate into ventricular fibrillation and lead to sudden death
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Ontology Term
- | Hearing
Description: Protein involved in hearing, the special sense by which an organism is able to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound
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Ontology Term
- | Plasmid
Description: Protein encoded on a plasmid, a self-replicating circular DNA that is found in a variety of bacterial, archaeal, fungal, algal and plant species, and can be transferred from one organism to another. Plasmids often carry antibiotic-resistant genes and are widely used in molecular biology as vectors of genes and in cloning
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Ontology Term
- | Ionotropic glutamate receptor inhibitor
Description: Protein that inhibits ionotropic glutamate receptor (iGluR). iGluRs are glutamate-gated ion channels that mediate excitatory neurotransmission in the central nervous system. Based on both molecular and pharmacological criteria, iGluRs have been divided into two major classes, the non-NMDA class, which includes both AMPA and kainate subtypes of receptors, and the NMDA class
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Ontology Term
- | TPQ
Description: Protein which is posttranslationally modified on a tyrosine residue to form TPQ. This modification of a strictly conserved active-site tyrosine residue proceeds via the hydroxylation of tyrosine to Topa (Trihydroxyphenylalanine) and then to TPQ (Topaquinone). It is a self- processing pathway requiring only the protein, copper and molecular oxygen. TPQ is the redox cofactor of most copper-containing amine oxidases
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Ontology Term
- | Respiratory chain
Description: Protein involved in respiratory chain. In aerobic respiration electrons are transferred from metabolites to molecular oxygen through a series of redox reactions mediated by an electron transport chain The resulting free energy is used for the formation of ATP and NAD. In anaerobic respiration analogous reactions take place with an inorganic compound other than oxygen as ultimate electron acceptor
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Ontology Term
- | Cytoplasm
Description: Protein found in the cytoplasm, the content of a cell within the plasma membrane and, in eukaryotics cells, surrounding the nucleus This three-dimensional, jelly-like lattice interconnects and supports the other solid structures. The cytosol (the soluble portion of the cytoplasm outside the organelles) is mostly composed of water and many low molecular weight compounds. In eukaryotes, the cytoplasm also contains a network of cytoplasmic filaments (cytoskeleton)
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Ontology Term
- | Photosystem II
Description: Protein involved in photosystem II (PSII), a complex that uses light energy to mediate electron flow in the chloroplast thylakoid membrane of plants and in cyanobacteria. PSII splits water, releasing hydrogen ions and molecular oxygen. PSII cannot use photons of a wavelength greater than 680 nm, and is thus sometimes called P680. PSII is a quinone type rection center (RC), sharing a common ancestor with the RCs of purple bacteria
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