DB identifier | AT5G42750 | Secondary Identifier | locus:2165472 |
Name | BRI1 kinase inhibitor 1 | Brief Description | BRI1 kinase inhibitor 1 |
TAIR Computational Description | BRI1 kinase inhibitor 1;(source:Araport11) |
TAIR Curator Summary | Encodes a plasma-membrane associated phosphoprotein that interacts directly with the kinase domain of BRI1 through the evolutionarily conserved C-terminal BIM motif binding to the C-lobe of the BRI1 kinase domain. It interferes with the interaction between BRI1 with its signalling partner, the plasma membrane localised LRR-receptor kinase BAK1 by inhibiting the transphosphorylation to keep BRI1 at a basal level of activity. It is phosphorylated by BRI1 at Ser270 & Ser274 and at tyrosine site Tyr211 and dissociates from plasma membrane to end up in the cytosol after phosphorylation. Its loss-of-function mutant shows higher sensitivity to BR treatment. |
TAIR Short Description | BRI1 kinase inhibitor 1 |
TAIR Aliases | BKI1 |