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Gene : SMG7 A. thaliana

DB identifier	AT5G19400	Secondary Identifier	locus:2150280
Brief Description	Telomerase activating protein Est1

TAIR Computational Description	Telomerase activating protein Est1;(source:Araport11)
TAIR Curator Summary	Encodes SMG7, a protein that possesses an evolutionarily conserved EST1 domain and exhibits strong homology to human SMG6 (EST1A) and SMG7 (EST1C) proteins. SMG7 plays an evolutionarily conserved role in nonsense-mediated RNA decay (NMD). Required for exit from meiosis. Hypomorphic smg7 alleles render mutant plants sterile by causing an unusual cell-cycle arrest in anaphase II that is characterized by delayed chromosome decondensation and aberrant rearrangement of the meiotic spindle. Disruption of SMG7 causes embryonic lethality.
TAIR Short Description	Telomerase activating protein Est1
TAIR Aliases	SMG7

4 Gene Rifs

1 Organism

13 Publications

0 Synonyms

Genomics

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21 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

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2 Proteins

Function

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Interactions

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Expression

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Homology

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0 Homologues

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9 Data Sets

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